摘要 |
<p>Disclosed is a novel compound having a xanthine oxidase inhibitory activity. Also disclosed is a pharmaceutical composition which contains such a compound as an active ingredient. Specifically disclosed is a nitrogen-containing heterocyclic compound represented by the general formula (I) below or the like, a pharmaceutically acceptable salt thereof, or a pharmaceutical composition containing any of them as an active ingredient.(I) (In the formula, Y<SUP>1</SUP> represents N or C(R<SUP>4</SUP>); Y<SUP>2</SUP> represents N or C(R<SUP>5</SUP>); R<SUP>4</SUP> and R<SUP>5</SUP> independently represent an alkyl group, a hydrogen atom or the like; one of R<SUP>1</SUP> and R<SUP>2</SUP> represents an optionally substituted aryl group, an alkoxy group or an optionally substituted heterocyclic group; the other one of R<SUP>1</SUP> and R<SUP>2</SUP> represents a haloalkyl group, a cyano group, a halogen atom or the like; and R<SUP>3</SUP> represents a 5-tetrazolyl group or a carboxy group.)</p> |
申请人 |
KISSEI PHARMACEUTICAL CO., LTD.;KIKUCHI, NORIHIKO;TAKIGAWA, YASUSHI;SHIMIZU, KAZUO;FUJIKURA, HIDEKI;IIZUKA, MASATO;TOYOSHIMA, TAKAHIRO;SASAKI, TOSHINOBU;HOSHINO, CHIKARA;TAKEDA, MASAKAZU |
发明人 |
KIKUCHI, NORIHIKO;TAKIGAWA, YASUSHI;SHIMIZU, KAZUO;FUJIKURA, HIDEKI;IIZUKA, MASATO;TOYOSHIMA, TAKAHIRO;SASAKI, TOSHINOBU;HOSHINO, CHIKARA;TAKEDA, MASAKAZU |