| 摘要 |
1,149,369. Extract of bark of Ravensara aromatica. FARBWERKE HOECHST A.G. 22 Sept., 1966 [22 Sept., 1965], No. 42344/66. Heading C2C. A novel compound which is an extract of the bark of Ravensara aromatica and has the following characteristics: composition C: 61À6%, H: 10À6%, 0: 27À1%; b.p. 67‹ C/l mm. Hg; U.V. maxima at 225, 278 and 284 mÁ; 2,4- dinitrophenylhydrazide m.p. 159‹ C.; NaHSO 3 adduct has m.p. 194‹ C. (decomposition), is is obtained either by steam distillation of the crushed bark or by extraction of the bark with an organic solvent e.g. ether after optionally previously extracting it with petroleum ether and in both cases further purifying the extract or steam distillate by distillation or chromatography. Pharmaceutical compositions for oral or intraarterial administration and having spasmolytic and coronaro-dilatatory activity comprise the above novel extract and a suitable pharmaceutical carrier therefor. |
