发明名称 |
Methods for Identifying Modulators of Protein Kinase C-Epsilon (Pkce) and Method of Treatment of Aberrant Glucose Metabolism Associated Therewith |
摘要 |
The present invention provides novel cell-based and animal-based assays for determining antagonists of PKCepsilon and uses of the isolated antagonist compounds for modulating insulin clearance and secretion. The invention also provides novel animals and cells such as animals and cells suitable for use in the assays.
|
申请公布号 |
US2008263689(A1) |
申请公布日期 |
2008.10.23 |
申请号 |
US20040572110 |
申请日期 |
2004.09.16 |
申请人 |
GARVAN INSTITUTE OF MEDICAL RESEARCH |
发明人 |
BIDEN TREVOR JOHN;SCHMITZ-PEIFFER CARSTEN |
分类号 |
A01K67/027;A61K31/711;A61K38/00;A61K38/08;A61K38/10;A61K38/17;A61K38/45;A61K48/00;A61P3/00;A61P3/10;C12N5/08;C12N9/12;C12Q1/02;C12Q1/48;C12Q1/68;G01N33/50;G01N33/53 |
主分类号 |
A01K67/027 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|