REDUCED PHOSPHOTRANSFERASE SYSTEM ACTIVITY IN BACTERIA
摘要
<p>A method of producing biological products using bacteria with an inactivated ptsHI and wild type err and no added glucose transport activity and which consumes nearly all glucose in the media is described. The ?ptsHI bacteria produce large quantities of recombinant protein without producing significant amounts of acetate. The bacteria grow well on standard LB broth without additional supplementation.</p>
申请公布号
WO2008128234(A1)
申请公布日期
2008.10.23
申请号
WO2008US60383
申请日期
2008.04.15
申请人
RICE UNIVERSITY;WONG, MATTHEW, SING;SAN, KA-YIU;BENNETT, GEORGE, N.;CAUSEY, THOMAS, BRYCE;WU, STEVEN
发明人
SAN, KA-YIU;BENNETT, GEORGE, N.;CAUSEY, THOMAS, BRYCE;WONG, MATTHEW, SING;WU, STEVEN