发明名称 |
METHODS FOR IDENTIFYING INHIBITORS OF SOLUTE TRANSPORTERS |
摘要 |
Provided herein are methods for identifying and characterizing agents that alter the volume of a cell. Methods are provided for rapid screening and identification of an agent that alters the capability of a small, neutrally charged solute transporter to transport the solute across a cell membrane. The methods described herein may be used to identify and characterize inhibitors of urea transporters, to identify and characterize inhibitors of aquaporins, and to identify and characterize inhibitors of other small, neutrally charged solutes such as glucose. |
申请公布号 |
WO2008067196(A3) |
申请公布日期 |
2008.10.23 |
申请号 |
WO2007US85017 |
申请日期 |
2007.11.16 |
申请人 |
VERKMAN, ALAN, S.;LEVIN, MARC, HARRIS |
发明人 |
VERKMAN, ALAN, S.;LEVIN, MARC, HARRIS |
分类号 |
G01N33/62;G01N33/50;G01N33/68;G01N33/80 |
主分类号 |
G01N33/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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