| 摘要 |
a method for replication of a nucleic acid; and a novel artificial base pair. The method is characterized by using a deoxyribonucleoside 5'-phosphate having a hydroxyl group at gamma-position in the phosphate substituted by a group selected from the group consisting of an amino group, a methylamino group, a diemthylamino group, a mercapto group and a fluoro group as a substrate in a replication reaction. The novel artificial base pair is characterized in that a base pair is formed between 7-(2-thienyl)-imidazo[4,5-b]pyridine (Ds) or an analogue thereof and pyrrole-2-carbaldehyde (Pa) or an analogue thereof. |
