| 发明名称 |
Novel kappa receptor selective opioid peptides |
| 摘要 |
<p>The present invention provides novel opioid peptides which are selective for the kappa opiate receptor. In one embodiment, the kappa-selective opioid peptides have the general structure (D)Phe-D4-E5-F6 (SEQ ID NO. 29), wherein D4 is (D)NapAla or (D)Phe, E5 is (D)Nle, Trp, or (D)Ile, and F6 is (D)Arg or (D)ChAla.</p> |
| 申请公布号 |
EP1978025(A1) |
申请公布日期 |
2008.10.08 |
| 申请号 |
EP20080002484 |
申请日期 |
1996.06.03 |
| 申请人 |
TORREY PINES INSTITUTE FOR MOLECULAR STUDIES |
发明人 |
DOOLEY, COLETTE T.;HOUGHTEN, RICHARD A. |
| 分类号 |
A61K38/00;C07K7/06;A61K31/00;A61K38/07;A61K38/08;A61P25/00;A61P25/02;C07K5/10;C07K5/103;C07K5/107;C07K14/665 |
主分类号 |
A61K38/00 |
| 代理机构 |
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