发明名称 |
ANTICANCER AGENT COMPRISING A PEPTIDE |
摘要 |
<p>Disclosed are peptides having SEQ ID NOs: 1 to 24 that induce superoxide generation by human monocytes or neutrophils; that induce an intracellular calcium increase by human peripheral blood monocytes or neutrophils; binds to formyl peptide receptor or formyl peptide receptor-like 1; that induce chemotactic migration of human monocytes or neutrophils in vitro; that induce degranulation in formyl peptide receptor expressing cells or formyl peptide receptor-like 1 expressing cells; that stimulate extracellular signal regulated protein kinase phosphorylation via activation of formyl peptide receptor or formyl peptide receptor-like 1; or that stimulate Akt phosphorylation via activation of formyl peptide receptor or formyl peptide receptor-like 1.</p> |
申请公布号 |
EP1976545(A1) |
申请公布日期 |
2008.10.08 |
申请号 |
EP20060835422 |
申请日期 |
2006.12.26 |
申请人 |
POSCO;POSTECH FOUNDATION |
发明人 |
RYU, SUNG-HO;SUH, PANN-GHILL;BAE, YOE-SIK;SONG, JI-YOUNG |
分类号 |
A61K38/08;A61P35/00 |
主分类号 |
A61K38/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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