Detection of ESR1 amplification in endometrium cancer and ovary cancer
摘要
The present invention relates to an in-vitro method of identifying a tumor resulting from a proliferative disease of the endometrium or ovary as responsive to anti-estrogen treatment. Further, the invention relates to an in-vitro method of identifying a candidate patient with a proliferative disease of the endometrium or ovary as suitable for anti-estrogen treatment. In a further aspect, the invention provides an in-vitro method of identifying an individual with a non-cancerous proliferative disease of the endometrium or ovary who is at risk of developing endometrial or ovarian cancer. The invention also provides kits for performing the above methods.
申请公布号
EP1978106(A1)
申请公布日期
2008.10.08
申请号
EP20070105836
申请日期
2007.04.07
申请人
UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF
发明人
SIMON, RONALD;SAUTER, GUIDO;TERRACCIANO, LUIGI;HOLST, FREDERIK;LEBEAU, ANNETTE;TURZYNSKI, ANDREAS