发明名称 |
Substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists |
摘要 |
Disclosed are compounds that are bradykinin B<SUB>1 </SUB>receptor antagonists and are useful for treating diseases, or relieving adverse symptoms associated with disease conditions, in mammals mediated by bradykinin B<SUB>1 </SUB>receptor. Certain of the compounds exhibit increased potency and are also expected to exhibit increased duration of action.
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申请公布号 |
US7432379(B2) |
申请公布日期 |
2008.10.07 |
申请号 |
US20040837231 |
申请日期 |
2004.04.30 |
申请人 |
ELAN PHARMACEUTICALS, INC. |
发明人 |
TUNG JAY S.;GAROFALO ALBERT W.;PLEISS MICHAEL A.;WU JING;WONE DAVID W. G.;GUINN ASHLEY C.;DRESSEN DARREN B.;NEITZ R. JEFFREY;MARUGG JENNIFER;NEITZEL MARTIN |
分类号 |
C07D401/12;A61P29/00;C07D231/16;C07D231/40;C07D401/14;C07D403/12;C07D409/12;C07D413/12;C07D417/12;C07D453/02;C07D471/04;C07D471/08;C07D487/08 |
主分类号 |
C07D401/12 |
代理机构 |
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代理人 |
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地址 |
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