Multiple layer polymeric structure

摘要

The present invention provides a receptacle ( 30 ) for a therapeutic fluid susceptible to deterioration on exposure to a gas such as oxygen or carbon dioxide. The receptacle ( 30 ) has walls of sheet material each including at least one layer forming a barrier essentially impermeable to such gas, and a seal sealing the walls together in a region thereof. A transfer tube ( 40 ) is sealed in the seal having a proximal end in the receptacle ( 30 ), a distal end accessible from outside the receptacle ( 30 ), a flow passage ( 56 ) extending between said proximal and distal ends, and a closure ( 54 ) blocking flow through the flow passage ( 56 ) adapted to be pierced by a tubular needle for transfer of therapeutic through the needle. The transfer tube ( 40 ) and closure ( 54 ) are essentially impermeable to said gas.