发明名称 |
ANTIBODIES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME USEFUL FOR INHIBITING ACTIVITY OF METALLOPROTEINS |
摘要 |
The present invention relates to a compound having the general Formula: ( I); wherein: m and n are each independently an integer from 1 to 6; X1-X3 an d Y1 -Y3 are each independently O or S; R1-R3 are each independently selecte d from the group consisting of hydrogen, alkyl, and cycloalkyl; and i R is ( CH2)x-C(-O)NR'-(CH2)y-NR'R" whereas: x and y are each independently an integ er from 1 to 6; and R' and R" arc each independently selected from the group consisting of, hydrogen, alkyl, and cycloalkyl; and to an antibody comprisi ng an antigen recognition region capable of specifically binding the above c ompound. |
申请公布号 |
CA2678304(A1) |
申请公布日期 |
2008.08.28 |
申请号 |
CA20082678304 |
申请日期 |
2008.02.21 |
申请人 |
YEDA RESEARCH AND DEVELOPMENT CO. LTD. |
发明人 |
KIKKERI, RAGHAVENDRA;SAGI, IRIT;ARAD-YELLIN, RINA;DANON, TAMAR;SELA, NETTA;SHANZER, ABRAHAM |
分类号 |
C07D233/61;A61K39/395;C07K16/40;C07K16/44 |
主分类号 |
C07D233/61 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|