发明名称 ANTIBODIES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME USEFUL FOR INHIBITING ACTIVITY OF METALLOPROTEINS
摘要 The present invention relates to a compound having the general Formula: ( I); wherein: m and n are each independently an integer from 1 to 6; X1-X3 an d Y1 -Y3 are each independently O or S; R1-R3 are each independently selecte d from the group consisting of hydrogen, alkyl, and cycloalkyl; and i R is ( CH2)x-C(-O)NR'-(CH2)y-NR'R" whereas: x and y are each independently an integ er from 1 to 6; and R' and R" arc each independently selected from the group consisting of, hydrogen, alkyl, and cycloalkyl; and to an antibody comprisi ng an antigen recognition region capable of specifically binding the above c ompound.
申请公布号 CA2678304(A1) 申请公布日期 2008.08.28
申请号 CA20082678304 申请日期 2008.02.21
申请人 YEDA RESEARCH AND DEVELOPMENT CO. LTD. 发明人 KIKKERI, RAGHAVENDRA;SAGI, IRIT;ARAD-YELLIN, RINA;DANON, TAMAR;SELA, NETTA;SHANZER, ABRAHAM
分类号 C07D233/61;A61K39/395;C07K16/40;C07K16/44 主分类号 C07D233/61
代理机构 代理人
主权项
地址