PROCESS FOR THE PREPARATION OF ESOMEPRAZOLE MAGNESIUM DIHYDRATE

摘要

A process for preparing Form A of (S) -5-methoxy-2- [ [ (4-methoxy-3, 5-d imethyl-2-pyridinyl) - methyl] sulf inyl] -1 H-benzimidazole magnesium dihyd rate, processes for preparing various intermediates useful in the preparatio n of Form A of (S) -5-methoxy-2- [ [ (4-methoxy-3, 5-dimethyl-2-pyridinyl) - methyl] sulf inyl] -1 H-benzimidazole magnesium dihydrate and a novel polymo rphic Form II of 5-methoxy-2- [ [ (4-methoxy-3, 5-dimethyl-2-pyridinyl) -met hyl] thio] -1 H-benzimidazole