| 摘要 |
It is intended to provide a hair growth promoter, a hair regrowth promoter, or a remedy for alopecia by determining an endogenous factor that inhibits hair growth and screening a substance that inhibits the activity or expression of the endogenous factor. FGF18 was found to inhibit hair growth, and a method in which an inhibitor of FGF18 activity or an inhibitor of FGF18 gene expression is screened, and the inhibitor is used as a candidate for a hair growth promoter, a hair regrowth promoter, and a remedy for alopecia is disclosed. Further, a hair growth promoter, a hair regrowth promoter, or a remedy for alopecia containing an inhibitor of FGF18 activity and/or an inhibitor of expression thereof such as a partial peptide of FGF18 or a hot water extract of momordica charantia as an active ingredient is disclosed. |
| 申请人 |
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCEAND TECHNOLOGY;IMAMURA, TORU;KIMURA, MIHO;KAWANO, MITSUKO;TSUJINO, NOZOMI;KURAMOCHI, AKIKO;ODA, YUKO;MOTOMURA, KAORI;SUZUKI, MASASHI;ASADA, MASAHIRO;KAMEYAMA, AZUSA;TOGAYACHI, SUMIE;OKA, SYUICHI |
发明人 |
IMAMURA, TORU;KIMURA, MIHO;KAWANO, MITSUKO;TSUJINO, NOZOMI;KURAMOCHI, AKIKO;ODA, YUKO;MOTOMURA, KAORI;SUZUKI, MASASHI;ASADA, MASAHIRO;KAMEYAMA, AZUSA;TOGAYACHI, SUMIE;OKA, SYUICHI |
