| 摘要 |
A method and device for thermolphoretic fluid or drug delivery through the creation of a thermal gradient in the skin. The device includes a heat generating mechanism capable of transdermal delivery of a beneficial agent, an insulating portion coupled with the heat generating mechanism, a cold generating mechanism coupled with the insulating portion, and wherein the heat generating mechanism and the cold generating mechanism create a thermal potential across dermal regions. The method includes generating a hot dermal region and transdermally delivering a beneficial agent, insulating, generating a cold dermal region, and creating a thermal potential across the hot dermal region and the cold dermal region.
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