COMPOSITIONS AND METHODS FOR MODULATING THE IMMUNE RESPONSE AND IDENTIFYING IMMUNOMODULATORS
摘要
<p>The present invention provides compositions and methods for the identification of immmunomodulators. The invention further provides an isolated complex comprising an UNC93B polypeptide and an UNC93B-dependent TLR polypeptide and methods of use thereof. The invention further provides methods of modulating immune system activity and methods of treating diseases characterized by aberrant immune system activity.</p>
申请公布号
WO2008103966(A2)
申请公布日期
2008.08.28
申请号
WO2008US54809
申请日期
2008.02.22
申请人
WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH;KIM, YOU-ME;BRIKMANN, MELANIE, M.;PLOEGH, HIDDE, L.
发明人
KIM, YOU-ME;BRIKMANN, MELANIE, M.;PLOEGH, HIDDE, L.
