Column system for creating a solution with high specific activity

摘要

The procedure for the production of radioactive daughter nuclide for medical applications, comprises allocating a generator with a chromatography column (3) having a stationary phase and an adsorbed mother nuclide at the stationary phase, eluting the daughter nuclides from the column with 0.9% of sodium chloride solution as solvent, filling the column with mother nuclides in a solution, oxidizing the solution with hydrogen peroxide and then acidifying with hydrochloric acid. The quantity of the adsorbed mother nuclides is 10% of the maximum adsorption capacity of the stationary phase. The procedure for the production of a radioactive daughter nuclide for medical applications, comprises allocating a generator with a chromatography column (3) having a stationary phase and an adsorbed mother nuclide at the stationary phase, eluting the daughter nuclides from the chromatography column with 0.9% of sodium chloride solution as solvent, filling the column with mother nuclides in a solution, oxidizing the solution with hydrogen peroxide and then acidifying with hydrochloric acid. The quantity of the adsorbed mother nuclides is 10% of the maximum adsorption capacity of the stationary phase. The chromatography column is filled with oxides of aluminum, zirconium, manganese or titanium or its mixture. The mother nuclide is tungston-188 in an acidic solution of sodium tungstate (Na 2 1> 8> 8>WO 4) that decomposes in rhenium-188. An independent claim is included for a generator for radioactive substances with a chromatography column.