| 发明名称 |
PYRAZOLOBENZODIAZEPINES AS CDK2 INHIBITORS |
| 摘要 |
Novel pyrazolobenzodiazepines having formula (I) and the pharmaceutically acceptable salts thereof, wherein R1, R2, R3 and R4 are as defined herein inhibit cyclin-dependent kinases (CDKs), in particular CDK2, are anti- proliferative agents useful in the treatment or control of cell proliferative disorders, in particular breast, colon, lung and prostate tumors.
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| 申请公布号 |
CA2367704(C) |
申请公布日期 |
2008.06.17 |
| 申请号 |
CA20002367704 |
申请日期 |
2000.04.14 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
WEI, CHUNG-CHEN;WOVKULICH, PETER MICHAEL;PIZZOLATO, GIACOMO;MADISON, VINCENT STEWART;DING, QINGJIE;LIU, JIN-JUN |
| 分类号 |
C07D487/04;A61K31/55;A61K31/5517;A61P1/00;A61P11/00;A61P13/08;A61P35/00;C07D243/22 |
主分类号 |
C07D487/04 |
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