发明名称 SULFOXIDE COMPOUNDS AND ACETONE COMPLEXES, AND A PROCESS FOR PRODUCING THE SAME
摘要 The present invention provides acetone complexes of sulfoxide compounds, useful as medicines such as inhibitors of gastric acid secretion and anti-ulcer agents or as intermediates for production of medicines, a process for producing the same and a purification method of using the same. Namely, it is the acetone complexes of sulfoxide compounds or of pharmaceutically acceptable salts thereof represented by the following formula: <IMG> (wherein R1 represents a hydrogen atom, a methoxy group or a difluoromethoxy group, R2 represents a methyl group or a methoxy group, R3 represents a 3 -methoxypropoxy group, a methoxy group or a 2,2,2 - trifluoroethoxy group, R4 represents a hydrogen atom or a methyl group, n and m independently represent an integer of 1 to 4, and B represents a hydrogen atom, an alkali metal atom or 1/2 alkaline earth metal atom), which are obtained by treating the sulfoxide compounds or pharmaceutically acceptable salts thereof with acetone.
申请公布号 CA2289409(C) 申请公布日期 2008.06.17
申请号 CA19992289409 申请日期 1999.11.15
申请人 EISAI CO., LTD. 发明人 NOCHI, SHIGEHARU;TSUJII, MASAHIKO;TAKAYANAGI, KEIZO;NIIKAWA, NOBUO
分类号 C07D401/12 主分类号 C07D401/12
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