| 摘要 |
A compound or salt thereof which has antioxidant activity and is effective in the treatment of ischemic organ diseases including arteriosclerosis, heart infarction, and brain infarction, in the treatment of diseases caused by oxidative cellular disorders, such as kidney diseases, and in the inhibition of retinal disorders caused by oxidation due to light, etc. Also provided is an antioxidant drug containing at least one of the compound and salt as an active ingredient. The compound is represented by the formula (1). The antioxidant drug is characterized by containing at least one of the compound and salt as an active ingredient. {In the formula (1), a is 1 or 2, R0 represents (un)substituted amino, R1 to R4 each independently represents hydrogen or alkyl, E represents an (un)substituted alkylene chain, D represents a single bond, oxygen, (un)substituted nitrogen, sulfur, sulfinyl, sulfonyl, carbonyl, carbonylamino, or aminocarbonyl, and A represents an (un)substituted aromatic hydrocarbon group, (un)substituted heterocyclic group, (un)substituted aralkyl, or (un)substituted heteroaralkyl.}
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