| 摘要 |
Disclosed is a process for the production of acetylpyridines of the formula (I), by reacting a pyridinecarboxylic ester of the formula (II), where R<1> is C1-6-alkyl, with acetic acid in the gas phase in the presence of a catalyst. The active material of the catalyst comprises titanium dioxide and at least one alkali or alkaline earth metal oxide and it is supported on an alumina-silica support having an apparent porosity of at least 50%. The process has the advantage of producing only small amounts of by-products (e.g., pyridine). |
