发明名称 |
Process for the preparation of L-carnitine inner salt, intermediates and their use |
摘要 |
<p>Process for the preparation of L-carnitine inner salt comprising the reduction with diborane, lithium borohydride, sodium borohydride, or with a mixed hydride of the COX2 group of a compound of formula (I), wherein said reduction is carried out at - 15 °C, and subsequent treatment with a base and then with trimethylamine. Also described are derivatives of succinic acid for use in the preparation of L-carnitine inner salt and their use.</p> |
申请公布号 |
SK286155(B6) |
申请公布日期 |
2008.04.07 |
申请号 |
SK20010001601 |
申请日期 |
2000.05.12 |
申请人 |
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. |
发明人 |
MELLONI PIERO;CERRI ALBERTO;SANTAGOSTINO MARCO |
分类号 |
C07D307/60;C07B53/00;C07C51/363;C07C51/377;C07C51/48;C07C51/56;C07C55/32;C07C55/40;C07C69/63;C07C227/08;C07C227/30;C07C227/32;C07C229/22;C07C309/66 |
主分类号 |
C07D307/60 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|