发明名称 |
ANTI-IL-22RA ANTIBODIES AND BINDING PARTNERS AND METHODS OF USING IN INFLAMMATION |
摘要 |
The present invention relates to blocking, inhibiting, reducing, antagonizing or neutralizing the activity of IL-22, IL-20, or both IL-20 and IL-22 polypeptide molecules. IL-20 and IL-22 are cytokines that are involved in inflammatory processes and human disease. IL-22RA (zcytor11) is a common receptor for IL-20 and IL-22. The present invention includes anti-IL-22RA antibodies and binding partners, as well as methods for antagonizing IL-22 or both IL-20 and IL-22 using such antibodies and binding partners. |
申请公布号 |
EA009026(B1) |
申请公布日期 |
2007.10.26 |
申请号 |
EA20050001505 |
申请日期 |
2004.03.24 |
申请人 |
ZYMOGENETICS, INC. |
发明人 |
XU WENFENG;KINDSVOGEL WAYNE;CHANDRASEKHER YASMIN, A.;DILLON STACEY, R.;LEHNER JOYCE, M.;SIADAK ANTHONY, W.;SIVAKUMAR PALLAVUR, V.;MOORE MARGARET, D. |
分类号 |
C07K16/28;C07K14/54;C07K14/715;C07K16/24 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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