发明名称 |
Detecting DNA sequence variations |
摘要 |
A method of analysing a polynucleotide target involves incubating the target with an oligonucleotide probe, generally an array of immobilised oligonucleotide probes, to form a duplex, and using ligase or polymerase to extend one chain of the duplex. A point mutation or variable number tandem repeat section may be analysed. Arrays of immobilised oligonucleotides are provided for use in the method.
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申请公布号 |
US2007111235(A1) |
申请公布日期 |
2007.05.17 |
申请号 |
US20060516521 |
申请日期 |
2006.09.07 |
申请人 |
SOUTHERN EDWIN M;PRITCHARD CLARE E;CASE-GREEN STEPHEN C |
发明人 |
SOUTHERN EDWIN M.;PRITCHARD CLARE E.;CASE-GREEN STEPHEN C. |
分类号 |
C12Q1/68;C12P19/34;G01N33/53;G01N37/00 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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