Piperidine compound and process for preparing the same

摘要

Disclosed are a novel piperidine compound represented by the general formula [I] below which has an excellent tachykinin receptor antagonizing activity and pharmacologically acceptable salts thereof. [I] In the formula, ring A represents an optionally substituted benzene ring; ring B represents an optionally substituted benzene ring; R¹ represents an optionally substituted hydroxyl group, a thiol group having a substituent, a sulfonyl group having a substituent, or a group represented by the following formula [II]: wherein R¹¹ represents a carbonyl group having a substituent or a sulfonyl group having a substituent and R¹² represents a hydrogen atom or an optionally substituted alkyl group; R² represents a hydrogen atom or the like; Z represents an oxygen atom or a group represented by -N(R³)- wherein R³ represents an optionally substituted alkyl group or the like; R^4a represents an optionally substituted alkyl group; and R^4b represents an optionally substituted alkyl group.