摘要 |
PROBLEM TO BE SOLVED: To provide a pharmaceutical composition effective for the prevention and/or treatment of diseases such as arteriosclerosis, hyperlipemia and dyslipidemia to which the inhibition of cholesteryl ester transfer protein (CETP) is effective. SOLUTION: The pharmaceutical composition contains a compound expressed by general formula (I) (R<SP>1</SP>is an alkoxycarbonyl or the like; R<SP>2</SP>is an alkyl or the like; R<SP>3</SP>is hydrogen or the like; R<SP>4</SP>is an alkylene or the like; R<SP>5</SP>is a substituted heterocyclic group; R<SP>6</SP>, R<SP>7</SP>, R<SP>8</SP>and R<SP>9</SP>are each independently hydrogen, an alkyl, an alkoxy or the like; and R<SP>10</SP>is a (substituted)aromatic group or the like) or its pharmacologically permissible salt as an active component. COPYRIGHT: (C)2007,JPO&INPIT
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