发明名称 |
Procaspase 1 activation inhibitor |
摘要 |
A method and an agent for inhibiting the oligomerization of procaspase-1, a method and an agent for inhibiting the activation of procaspase-1, a method and an agent for inhibiting the production of caspase-1, a method of preventing and/or treating an inflammatory disease, and an agent for preventing and/or treating an inflammatory disease, all of which comprise inhibiting the binding of NOD2 to procaspase-1; a method of identifying a compound that inhibits the binding of NOD2 to procaspase-1; and a reagent kit for use in the identifying method are provided.
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申请公布号 |
US2007111934(A1) |
申请公布日期 |
2007.05.17 |
申请号 |
US20040580877 |
申请日期 |
2004.11.26 |
申请人 |
CELESTAR LEXICO-SCIENCES, INC., |
发明人 |
DOI HIROFUMI;MASUDA SHOICHI;ISUMI YOSHITAKA |
分类号 |
A61K38/55;A61K45/00;A61P1/00;A61P1/04;A61P29/00;A61P31/04;C07K14/47;C12N9/64;C12N15/12;C12N15/57;C12Q1/37 |
主分类号 |
A61K38/55 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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