摘要 |
<p>New dendrimers with bisphosphonic terminal groups. - The dendrimers of generation 0-12 consist of a central nucleus of valence or more, optionally arborescence generation chains around the nucleus, an intermediate chain around the nucleus or at the end of each generation chain and a terminal chain at the extremity of each intermediate chain. The terminal group is of Formula (T) (A1) less than (A2-P(=O), (OX)2)2 (T) - A1 = -CR less than , heteroatom less than ; - A2 = a simple bond, 1-6 link hydrocarbon chain each link being optionally a heteroatom and each optionally substituted with alkyl or halogen or -NO2 or -NRR' or -CN or -CF3 or -OH or Oalkyl or aryl or aralkyl; - X = alkyl, aryl, H, /M+; - M = cation; less than = two bonds on A1.</p> |