发明名称 PREPARATION OF PHARMACEUTICAL SALTS OF [1, 4] - BIPIPERIDINE.
摘要 The invention provides anhydrous and hydrated forms of sodium salt of N-[ [4- (3, 4-dichlorophenoxy) [1, 4'-bipiperidin] -1'-yl]carbonyl]-4-methyl -benzenesulfonamide and crystalline forms of N- [[4-(3, 4-dichlorophenoxy) [1, 4' -bipiperidin]- 1' -yl]carbonyl] -4-methyl-benzenesulfonamide; and such compounds are modulators of chemokine (especially CCR3) activity and are especially useful for treating asthma and/or rhinitis.
申请公布号 MXPA06004828(A) 申请公布日期 2006.07.03
申请号 MX2006PA04828 申请日期 2004.11.03
申请人 ASTRAZENECA AB 发明人 GERALD STEELE
分类号 A61K31/445;A61K31/4745;A61P11/06;A61P37/00;C07D;C07D401/04;C07D409/14;(IPC1-7):A61K31/445;A61K31/474 主分类号 A61K31/445
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