发明名称 |
Substituted phenylalkanoic acids |
摘要 |
The present invention relates to compounds and pharmaceutically acceptable salts of formula I: which are useful in the treatment of metabolic disorders related to insulin resistance or hyperglycemia. These compounds include inhibitors of protein tyrosine phosphatase (PTP-1B) that are useful in the treatment of diabetes and other PTP-1B mediated diseases, such as cancer, neurodegenerative diseases and the like. The compounds of the invention are also useful in pharmaceutical compositions and methods of treating the aforementioned conditions.
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申请公布号 |
US2006100251(A1) |
申请公布日期 |
2006.05.11 |
申请号 |
US20050262423 |
申请日期 |
2005.10.28 |
申请人 |
THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC |
发明人 |
VAN ZANDT MICHAEL C.;FANG HAIQUAN;HU SHAOJING;WHITEHOUSE DARREN |
分类号 |
A61K31/44;A61K31/195;C07C311/42;C07D213/55 |
主分类号 |
A61K31/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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