BUTYROPHENOMENES AND SIGMA-1 RECEPTOR ANTAGONISTS PROTECT AGAINST OXIDATIVES-STRESS

摘要

The present invention includes compositions and methods for the protection of one or more central nervous system cells from trauma, when administered before, during or after the trauma, wherein the composition includes an effective amount of a butyrophenone, e.g., a 1­-linked phenyl butyrophenone that is electronegative along the butyl chain and/or a Sigma-1 receptor antagonist.