发明名称 PIPERAZINYLPHENALKYL LACTAM/AMINE LIGANDS FOR THE 5HT1B RECEPTOR
摘要 <p>The present invention relates to novel derivatives, that are compounds of Formula (I), wherein R&lt;SUB&gt;1&lt;/SUB&gt;, R&lt;SUB&gt;2&lt;/SUB&gt;, R&lt;SUB&gt;3&lt;/SUB&gt;, R&lt;SUB&gt;14&lt;/SUB&gt;, X, Y, n and m are defined herein, their pharmaceutically acceptable salts, pharmaceutical compositions and methods using said compounds in treating or preventing depression, anxiety, obsessive compulsive disorder (OCD) and other disorders for which selective antagonists, inverse agonists and partial agonists of serotonin 1 (5-HT&lt;SUB&gt;1&lt;/SUB&gt;) receptors, specifically, antagonists of 5-HT&lt;SUB&gt;1B&lt;/SUB&gt; are useful.</p>
申请公布号 WO2006048727(A1) 申请公布日期 2006.05.11
申请号 WO2005IB03252 申请日期 2005.10.21
申请人 PFIZER PRODUCTS INC.;BUTLER, TODD, WILLIAM 发明人 BUTLER, TODD, WILLIAM
分类号 A61K31/4166;A61K31/4035;A61K31/4184;A61K31/4188;A61K31/513;A61K31/517;A61P25/00;C07D209/48;C07D209/66;C07D217/24;C07D233/70;C07D235/26;C07D239/10;C07D239/96;C07D471/04 主分类号 A61K31/4166
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