发明名称 SULFATE CONJUGATES OF URSODEOXYCHOLIC ACID, AND THEIR BENEFICIAL USE IN INFLAMMATORY DISORDERS AND OTHER APPLICATIONS
摘要 PROBLEM TO BE SOLVED: To provide a composition for preventing or treating the hepatic diseases of mammals. SOLUTION: UDCA-7-sulfate and UDCA-3,7-disulfate are used as a sulfate of 3 alpha, 7 beta-dihydroxy-5 beta-cholan-24-oic acid (UDCA) of active ingredient. A bile flux of the UDCA-7-sulfate and UDCA-3,7-disulfate is relatively larger than other sulfates and are secreted into a bile without being changed. COPYRIGHT: (C)2006,JPO&NCIPI
申请公布号 JP2006117698(A) 申请公布日期 2006.05.11
申请号 JP20060003753 申请日期 2006.01.11
申请人 CHILDREN'S HOSPITAL MEDICAL CENTER 发明人 SETCHELL KENNETH D R
分类号 A61K31/575;A61K47/24;A01N1/02;A61K31/00;A61P1/00;A61P1/04;A61P1/16;A61P29/00;A61P35/00 主分类号 A61K31/575
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