发明名称 |
Method for performing restrained dynamics docking of one or multiple substrates on multi-specific enzymes |
摘要 |
The present invention relates to a method for performing restrained dynamics docking of one or several substrates having allosteric or synergistic effect on enzymes presenting multipspecific and flexible active site. It also concerns a method for determining the 3D-substrates, which is the case for multispecific enzymes such as cytochrome P450, and specifically to cytochrome P450 3A4 and P450 3A7.
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申请公布号 |
US2006099667(A1) |
申请公布日期 |
2006.05.11 |
申请号 |
US20050532868 |
申请日期 |
2005.04.28 |
申请人 |
ANDRE FRANCOIS;DELAFORGE MARCEL;LOISEAU NICOLAS |
发明人 |
ANDRE FRANCOIS;DELAFORGE MARCEL;LOISEAU NICOLAS |
分类号 |
C12N9/02;C12Q1/26;G06F19/16 |
主分类号 |
C12N9/02 |
代理机构 |
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主权项 |
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地址 |
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