| 摘要 |
<p>The present invention discloses compounds of Formula I: (I) having 11beta -HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as the use of the Fomula I and compositions as medicaments to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, Syndrome X, and other conditions associated with hyperglycemia.</p> |
| 申请人 |
ELI LILLY AND COMPANY;AICHER, THOMAS, D.;CHICARELLI, MARK, JOSEPH;HINKLIN, RONALD, JAY;TIAN, HONGQI;WALLACE, OWEN, BRENDAN;CHEN, ZHAOGEN;MABRY, THOMAS, EDWARD;MCCOWAN, JEFFERSON, RAY;SNYDER, NANCY, JUNE;WINNEROSKI, LEONARD, LARRY, JUNIOR;ALLEN, JOHN, GORDON |
发明人 |
AICHER, THOMAS, D.;CHICARELLI, MARK, JOSEPH;HINKLIN, RONALD, JAY;TIAN, HONGQI;WALLACE, OWEN, BRENDAN;CHEN, ZHAOGEN;MABRY, THOMAS, EDWARD;MCCOWAN, JEFFERSON, RAY;SNYDER, NANCY, JUNE;WINNEROSKI, LEONARD, LARRY, JUNIOR;ALLEN, JOHN, GORDON |
