发明名称 |
ALIPHATIC AMINE POLYMER SALTS FOR TABLETING |
摘要 |
The tablets, compositions and methods of the present invention, comprising a carbonate salt of an aliphatic amine polymer and s monovalent anion can prevent or ameliorate acidosis, in particular acidosis in patients with renal disease. The tablets and compositions of the present invention maintain a disintegration time of no greater than 30 minutes at 37° C. and at pH of at least 1 for a period of at least ten weeks at 60° C. Furthermore, the tablets are stable for extended periods of time without the need for specialized storage conditions. |
申请公布号 |
CA2586023(A1) |
申请公布日期 |
2006.05.11 |
申请号 |
CA20052586023 |
申请日期 |
2005.11.01 |
申请人 |
GENZYME CORPORATION |
发明人 |
BRENNER, LOUIS;BHAGAT, HITESH;HARIANAWALA, ABIZER;GOLDBERG, JEFFREY MARC |
分类号 |
A61K9/20;A61K31/13 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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