摘要 |
Compounds represented by the formula: Wherein A is -(CH2)n-R, -CH=CH2, -CH2-CH=CH2, -O-(CH2)n-R, -CH(OH)CH3, -CH(OH)-CH2OH, -CH2-CH(OH)CH3, -CH2-CH(OH)-CH2OH, -CH(OH)-CH(OH)-CH3; R is H, OH, F, N3, NH2, CO2H, SH, alkyl, S-alkyl, O-acyl, CONH2, CONH-alkyl; Z and Z' independently is OR<1>, OR<2>, O-(CH2)n-O-alkyl or aminoacids and esters thereof; R<1 >and R<2 >independently is H, alkyl, aryl, pivaloyloxymethyl, phthalyl or substituted phthalyl, C(R<3>)2OC(O)X(R<4>)a, R<3 >is -H, C1-C12 alkyl, C5-C12 aryl, C2-C12 alkenyl, C2-C12 alkynyl, C7-C12 alkenylaryl, C7-C12 alkynylaryl, or C6-C12 alkaryl, any of which is unsubstituted or is substituted with 1 or 2 halo, cyano, azido, nitro, or -OR<5>; R<4 >is -H, C1-C12 alkyl, C5-C12 aryl, C2-C12 alkenyl, C2-C12 alkynyl, C7-C12 alkenylaryl, C7-C12 alkynylaryl, or C6-C12 alkaryl, any of which is unsubstituted or is substituted with 1 or 2 halo, cyano, azido, nitro, -N(R<6>)2 or -OR<5>; R<5 >is C1-C12 </subscri |