发明名称 IMIDAZOLE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS
摘要 <p>Therapeutic benzimidazoles and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.</p>
申请公布号 WO2006044527(A1) 申请公布日期 2006.04.27
申请号 WO2005US36800 申请日期 2005.10.14
申请人 AMGEN INC. 发明人 GORE, VIJAY KESHAV;MA, VU VAN;NORMAN, MARK H.;OGNYANOV, VASSIL I.;XI, NING
分类号 C07D401/12;A61K31/4168;A61P29/00;C07D233/88 主分类号 C07D401/12
代理机构 代理人
主权项
地址