PROCESS FOR PREPARING SOLID PHARMACEUTICAL DOSAGE FORM

摘要

PROBLEM TO BE SOLVED: To provide a process for preparation of an oral solid rapidly disintegrating dosage form of a pharmaceutically active substance with an unacceptable taste. SOLUTION: This invention relates to the process for the preparation of the solid pharmaceutical dosage form which process comprises forming a solution or a suspension in a solvent of a form of the pharmaceutically active substance which is less soluble in water and more palatable than the form with the unacceptable taste together with a water-soluble or water-dispersible carrier material, forming discrete units of the suspension or solution and removing the solvent from the discrete units under conditions in which a network of the carrier material carrying a dosage of the less soluble and more palatable form of the pharmaceutically active substance is formed. COPYRIGHT: (C)2006,JPO&NCIPI