MODULATION OF NEUROGLIA-DERIVED BDNF IN THE TREATMENT AND PREVENTION OF PAIN
摘要
<p>Methods and products for the treatment or prevention of pain and the reduction of nociception are described, comprising the modulation of neuroglia-derived brain-derived neurotrophic factor (BDNF) expression or activity in a mammalian host by the administration of an agent such as the P2X receptor inhibitor, TNP-ATP, a BDNF antisense molecule or BDNF siRNA. Related methods for identifying or characterizing compounds for the treatment or prevention of pain and the reduction of nociception are also described.</p>
申请公布号
WO2006042396(A1)
申请公布日期
2006.04.27
申请号
WO2005CA01501
申请日期
2005.09.30
申请人
UNIVERSITE LAVAL;THE HOSPITAL FOR SICK CHILDREN;COULL, JEFFREY, A., M.;DE KONINCK, YVES;SALTER, MICHAEL;BEGGS, SIMON
发明人
COULL, JEFFREY, A., M.;DE KONINCK, YVES;SALTER, MICHAEL;BEGGS, SIMON
