| 发明名称 |
МАЛОНАМИДНЫЕ ПРОИЗВОДНЫЕ В КАЧЕСТВЕ ИНГИБИТОРОВ ГАММА-СЕКРЕТАЗЫ |
| 摘要 |
The invention relates to malonamide derivatives of formula wherein each of the variables are as defined in the specification and to pharmaceutically acceptable acid addition salts thereof. The compounds are gamma-secretase inhibitors. Thus, the invention also relates to pharmaceutical compositions containing these compounds and to a method of treating Alzheimer's disease by administering the compounds of the invention. |
| 申请公布号 |
RU2005127666(A) |
申请公布日期 |
2006.04.27 |
| 申请号 |
RU20050127666 |
申请日期 |
2004.01.27 |
| 申请人 |
Ф.ХОФФМАНН-ЛЯ РОШ АГ (CH) |
发明人 |
ГАЛЛЕЙ Гуидо (DE);ГЕРГЛЕ Анник (FR);ЯКОБЗЕН Хельмут (DE);КИТАС Эрик Аргириос (CH);ПЕТЕРС Йенс-Уве (DE) |
| 分类号 |
C07D401/06;C07C237/12;C07C237/14;C07D209/18;C07D209/44;C07D215/22;C07D215/227;C07D217/06;C07D223/18;C07D243/12;C07D243/14;C07D243/24;C07D265/30;C07D401/04;C07D401/12;C07D403/06;C07D405/12;C07D409/12;C07D471/04;C07D471/06;C07D471/08;C07D487/06 |
主分类号 |
C07D401/06 |
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