METHOD FOR PRODUCING C1-C15 FRAGMENTS OF EPOTHILONES AND THE DERIVATIVES THEREOF.

摘要

The invention relates to a method for producing C1-C15 fragments of epothilones and the derivatives thereof, whereby a C1-C6 fragment is bonded to a C7-C12 fragment to form a C1-C12 fragment which is then converted with a C13-C15 fragment to form the C1-C15 epothilone intermediate product to be produced. The thus produced C1-C15 epothilone intermediate products can be converted into the intrinsic active ingredients according to known methods. The invention also relates to the corresponding C1-C12 fragments.