摘要 |
<p>In the present invention the methods for recognition of biologically active hepatocyte growth factor efficient for using in therapeutic components are presented. The biological activity can be determined using: i) an in vitro model of restitution of damaged cells, and/or ii) affinity measurements or epitope mapping using SPR, with the C-met receptor, ant i -HGF antibodies or polysaccharides such as dextran, and/or iii) .an animal model of hair growth rates. By these methods the activity of HGF in body secretions can be evaluated as well .</p> |