METHODS FOR THE PREPARATION OF ARYL PIPERAZINYL-HETEROCYCLIC COMPOUNDS

摘要

A novel method for preparing a compound of formula (I), which comprises of coupling the piperazine derivative of formula (II), with alkyl halide containing compound of the formula (III), by heating in solvent free conditions or, optionally, in a minimum quantity of non-aqueous suspending liquid, in presence of a catalyst and a neutralizing agent to neutralize the hydrohalic acid.