摘要 |
FIELD: organic chemistry, biochemistry. ^ SUBSTANCE: invention relates to some new macroheterocyclic compounds that can act as selective inhibitors of kinase or double kinase. Invention describes compounds of the following formulae: formula (Ia1), formula (Ib1), formula (If1), formula (Ii1), and formula (Ij1) wherein values R2, R4 and R5 are chosen by the dependent manner as given in the invention claim. Invention provides preparing new compounds possessing valuable biological properties. ^ EFFECT: valuable biological properties of compounds. ^ 5 cl, 3 tbl, 22 ex |