<p>The invention provides a gene silencing molecule, which is adapted to down-regulate expression of a gene encoding a peptide involved with the Rho-A inhibitory pathway. The gene silencing molecule is used to promote neuron survival and axon regeneration in the central nervous system (CNS). The invention also provides compositions and methods of using same to improve neural survival and promote axonal growth.</p>
申请公布号
WO2006043014(A1)
申请公布日期
2006.04.27
申请号
WO2004GB04504
申请日期
2004.10.22
申请人
NEUREGENIX LIMITED;AHMED, ZUBAIR;BERRY, MARTIN;LOGAN, ANN