发明名称 |
ENTERIC-COATED TABLETS OF PANTOPRAZOLE |
摘要 |
The invention relates to enteric-coated tablets containing pantoprazole as active ingredient and a process for the preparation thereof. The tablets according to the invention comprise a.) a core consisting of 20-50% by weight (related to the weight of the tablet core) of the active ingredient, spray-dried or granulated mannitol having an average particle size between 100 µm and 500 µm, an alkalizing agent, a disintegrant and a lubricant conventionally applied in the pharmaceutical industry; b.) a water-soluble separating film coating; c.) an enterosolvent film coating insoluble in gastric juices; and d.) an optional water-soluble protecting film coating, and show increased stability during storage. |
申请公布号 |
WO2005051348(A3) |
申请公布日期 |
2006.04.27 |
申请号 |
WO2004HU00111 |
申请日期 |
2004.11.24 |
申请人 |
EGIS GYOGYSZERGYAR RT.;FEKETE, PAL;SZLAVYNE SZELL, ZSUZSA;BURESNE PAPP, CECILIA;FURDYGA, EVA |
发明人 |
FEKETE, PAL;SZLAVYNE SZELL, ZSUZSA;BURESNE PAPP, CECILIA;FURDYGA, EVA |
分类号 |
A61K9/20;A61K9/28;A61K9/50;A61K31/44 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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