| 发明名称 |
2-thio-substituted imidazole derivatives and their use in pharmaceutics |
| 摘要 |
The invention relates to 2-thio-substituted imidazole derivatives of the formula I in which the radicals R<SUB>1</SUB>, R<SUB>2</SUB>, R<SUB>3</SUB>, R<SUB>4 </SUB>and p are as defined in the description. The compounds according to the invention have immunomodulating and/or cytokine-release-inhibiting action and are therefore suitable for treating disorders associated with a disturbed immune system.
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| 申请公布号 |
US7442713(B2) |
申请公布日期 |
2008.10.28 |
| 申请号 |
US20050514911 |
申请日期 |
2005.05.10 |
| 申请人 |
MERCKLE GMBH |
发明人 |
LAUFER STEFAN;STRIEGEL HANS-GUENTER;ALBRECHT WOLFGANG;TOLLMANN KAROLA |
| 分类号 |
A61K31/44;A61K31/4439;A61K31/4545;A61K31/5377;A61P1/00;A61P1/02;A61P1/04;A61P1/16;A61P1/18;A61P3/10;A61P7/00;A61P9/04;A61P9/08;A61P9/10;A61P11/00;A61P17/00;A61P17/06;A61P17/14;A61P19/02;A61P19/06;A61P19/10;A61P25/00;A61P25/04;A61P25/28;A61P29/00;A61P31/18;A61P35/00;A61P37/02;A61P43/00;C07D401/04;C07D401/14;C07D405/14 |
主分类号 |
A61K31/44 |
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