发明名称 |
TREATMENT OF NON ALCOHOLIC STEATOTIC HEPATITIS (NASH) |
摘要 |
<p>The present invention relates to a method for treating nonalcoholic steatotic hepatitis (NASH) in a subject by administering an effective amount of a lipoprotein lipase (LPL) therapeutic to the subject. The LPL therapeutic is advantageously a S447X protein or a derivative or variant thereof, or a nucleic acid encoding such a protein. The LPL therapeutic may be used in a gene therapy vector.</p> |
申请公布号 |
PT1761273(E) |
申请公布日期 |
2008.10.28 |
申请号 |
PT20050753069T |
申请日期 |
2005.06.20 |
申请人 |
AMSTERDAM MOLECULAR THERAPEUTICS B.V. |
发明人 |
SANDER JAN HENDRIK VAN DEVENTER |
分类号 |
A61K38/46;A61K48/00;A61P1/16;C12N15/864 |
主分类号 |
A61K38/46 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|