发明名称 CRYSTALS INCLUDING A MALIC ACID SALT OF N-[2-(DIETHYLAMINO)ETHYL]-5-[(5-FLUORO-2-OXO-3H-INDOLE-3-YLIDENE)METHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE, PROCESSES FOR ITS PREPARATION AND COMPOSITIONS THEREOF
摘要 The present invention provides crystals, and compositions thereof, wherein the crystals include a malic acid salt of N-[2-(diethylamino)ethyl]5-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide. Methods of preparing such crystals are also disclosed.
申请公布号 HU0700036(A2) 申请公布日期 2008.10.28
申请号 HU20070000036 申请日期 2002.08.13
申请人 PHARMACIA & UPJOHN COMPANY, KALAMAZOO 发明人 HAWLEY, MICHAEL;FLECK, THOMAS J.;PRESCOTT, STEPHEN P.;MALONEY, MARK T.
分类号 C07D403/06;A61K31/404;A61P17/06;A61P35/00;A61P35/02;A61P43/00;C07C59/245;C07D 主分类号 C07D403/06
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